| Characteristic | Details |
|---|---|
| Chemical Formula | C14H20Br2N2 |
| Molecular Weight | 376.13 g/mol |
| CAS Number | 3572-43-8 |
| Pregnancy Category | Not classified |
| Learn More About Bromhexine | |
Bromhexine is a mucolytic agent often employed in respiratory conditions. Its utility stems from its ability to disrupt mucus structures, facilitating easier expectoration. Available as Bromhexine 8mg, it serves a crucial role in alleviating symptoms of bronchopulmonary diseases. The compound ensures mucus clearance, thus enhancing pulmonary functions.
Chemical Structure
Bromhexine, a benzylamine derivative, possesses a brominated phenyl ring. This complex architecture is key to its pharmacological profile. The bromine atoms in the compound play a significant role. They increase the molecule’s lipophilicity. This aspect enhances its distribution across biological membranes. The structural design of Bromhexine supports its role in altering the consistency of bronchial secretions.
The crystalline nature of Bromhexine allows for its stability. This aspect ensures its efficacy in pharmaceutical formulations. Its molecular weight contributes to its favorable pharmacokinetic properties. The compound’s chemical robustness allows it to withstand various environmental conditions. This factor enhances its shelf life and usability in diverse therapeutic settings.
Mechanism of Action
Bromhexine acts by breaking down mucopolysaccharide fibers. This action reduces the viscosity of mucus. It promotes the clearance of respiratory pathways. The compound stimulates serous gland activity. It increases the volume and reduces the consistency of sputum. This dual action facilitates better airway function and eases breathing.
Additionally, Bromhexine enhances ciliary movement. This supports the removal of mucus from the respiratory tract. The stimulation of lysosomal activity aids in the degradation of mucin structures. These combined mechanisms provide significant relief in conditions with excessive mucus production.
FDA-Approved Indications
Bromhexine is indicated for a range of respiratory disorders. It is used primarily in bronchitis, asthma, and chronic obstructive pulmonary disease (COPD). The drug aids in the management of productive cough. It supports the clearance of bronchial secretions in conditions involving mucus accumulation.
While the FDA has not classified Bromhexine under pregnancy categories, it remains a staple in symptomatic management. Its use is largely governed by physician discretion, given its non-categorized status. Clinicians weigh its benefits against potential risks when considering it for pregnant individuals.
Pregnancy and Breastfeeding
Data on Bromhexine’s safety in pregnancy is limited. The compound lacks definitive classification under FDA pregnancy categories. Physicians must exercise caution when prescribing Bromhexine to expectant mothers. A thorough risk-benefit analysis is essential. While adverse effects are not common, the absence of extensive studies warrants careful consideration.
Regarding breastfeeding, Bromhexine’s excretion in breast milk is not well-documented. Lactating mothers should consult healthcare providers before use. The decision to continue Bromhexine during breastfeeding should involve careful evaluation of the therapeutic benefits versus potential risks to the infant.
Bromhexine Side Effects
Bromhexine is generally well-tolerated. Common side effects include gastrointestinal disturbances. Patients may experience nausea, diarrhea, or abdominal discomfort. These symptoms are often mild and transient.
Rarely, hypersensitivity reactions occur. These include skin rashes and urticaria. Severe allergic reactions, although uncommon, require immediate medical attention. Healthcare providers should inform patients about potential side effects to ensure prompt reporting and management.
Bromhexine Over the Counter
Bromhexine is available as an over-the-counter medication in many regions. It is accessible in various forms, including tablets and syrups. This availability facilitates easy access for individuals with chronic respiratory conditions.
However, patients should follow the recommended dosage instructions. Misuse or overuse can lead to adverse effects. It is advisable to consult a healthcare provider for guidance, especially in chronic use cases. The over-the-counter status of Bromhexine underscores its safety profile when used as directed.
| Symptom | Severity | Frequency |
|---|---|---|
| Nausea | Mild | Common |
| Diarrhea | Moderate | Occasional |
| Allergic Reaction | Severe | Rare |
In sum, Bromhexine remains a key therapeutic agent in respiratory care. Its action in reducing mucus viscosity enhances patient comfort and recovery. Despite the need for caution in pregnancy, its wide availability underscores its efficacy and safety. For those with chronic respiratory conditions, Bromhexine continues to provide essential relief.
Data origin:
- https://pusatsewasofa.com/interaksi-antara-larutan-oral-diazepam-dan-toksokariasis-toksocara/
- https://www.patrimoine.praxitele.fr/2023/12/19/faune-sauvage-soulagement-et-efficacite-de-la-congestion-nasale/
- https://farazinstruments.com/dichloroxylenol-evaluating-antimicrobial-potency-and-use/
- https://holidayssrilanka.com/dirofilariasis-dog-heartworm/
- https://digital.itsmeraja.com/rett-syndrome-and-dermatophyte-infection-management/
- https://kissbliss.online/nhiem-trung-adenovirus-va-dieu-tri-teo-co.html
- https://www.911mg.org/narcolepsy/provigil.htm
- https://arabrentacars.com/2024/08/13/measles-a-window-to-modern-vaccine-efficacy/
- https://afnanjanjua.com/wolfram-syndrome-and-seizure-management/
- https://apexcoachings.com/blogs/zenatane-implications-for-maternal-and-overall-health/